Motif ID: FOX{C1,C2}.p2
Z-value: 1.538
Transcription factors associated with FOX{C1,C2}.p2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| FOXC1 | 2296 | forkhead box C1 |
| FOXC2 | 2303 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXC1 | chr6_+_1610680 | -0.21 | 4.4e-01 | Click! |
| FOXC2 | chr16_+_86600856 | -0.18 | 5.0e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in process category:
Showing 1 to 5 of 5 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 27.41 | 2.57e-03 | GO:0010951 | negative regulation of endopeptidase activity |
| 13.13 | 4.66e-02 | GO:0051346 | negative regulation of hydrolase activity |
| 6.36 | 1.71e-02 | GO:0050817 | coagulation |
| 6.31 | 1.79e-02 | GO:0007599 | hemostasis |
| 5.36 | 4.95e-02 | GO:0042060 | wound healing |
Gene overrepresentation in compartment category:
Showing 1 to 11 of 11 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 24.49 | 1.38e-02 | GO:0031093 | platelet alpha granule lumen |
| 23.98 | 1.47e-02 | GO:0034774 | secretory granule lumen |
| 23.03 | 1.66e-02 | GO:0060205 | cytoplasmic membrane-bounded vesicle lumen |
| 22.14 | 1.86e-02 | GO:0031983 | vesicle lumen |
| 20.56 | 2.32e-02 | GO:0031091 | platelet alpha granule |
| 10.68 | 5.15e-03 | GO:0030141 | stored secretory granule |
| 7.85 | 2.17e-02 | GO:0005578 | proteinaceous extracellular matrix |
| 7.80 | 5.39e-03 | GO:0031012 | extracellular matrix |
| 4.64 | 1.23e-02 | GO:0005615 | extracellular space |
| 4.15 | 1.06e-02 | GO:0044421 | extracellular region part |
| 4.06 | 3.32e-05 | GO:0005576 | extracellular region |
Gene overrepresentation in function category:
Showing 1 to 6 of 6 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 35.96 | 4.26e-03 | GO:0005504 | fatty acid binding |
| 24.76 | 1.05e-03 | GO:0004867 | serine-type endopeptidase inhibitor activity |
| 23.03 | 1.63e-02 | GO:0033293 | monocarboxylic acid binding |
| 13.36 | 1.18e-02 | GO:0030414 | peptidase inhibitor activity |
| 13.02 | 1.31e-02 | GO:0061135 | endopeptidase regulator activity |
| 10.75 | 2.72e-02 | GO:0061134 | peptidase regulator activity |